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T9075

Sigma-Aldrich

Anti-TRPV4 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-OTRPC4, Anti-Transient Receptor Potential Channel V4

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About This Item

MDL number:
MFCD07370529
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

rat

technique(s)

western blot: 1:200 using ND7/23 (mouse neuroblastoma X rat DRG neuron hybrid cell line) lysate

UniProt accession no.

Q9ERZ8

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

rat ... Trpv4(66026)

Immunogen

synthetic peptide CDGHQQGYAPKWRAEDAPL corresponding to residues 853-871 of rat TRPV4.

Physical form

Lyophilized from phosphate buffered saline containing 1% BSA and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Bernd Nilius et al.
American journal of physiology. Cell physiology, 286(2), C195-C205 (2004-01-07)
The vanilloid receptor-1 (VR1, now TRPV1) was the founding member of a subgroup of cation channels within the TRP family. The TRPV subgroup contains six mammalian members, which all function as Ca2+ entry channels gated by a variety of physical
Guida Landouré et al.
Nature genetics, 42(2), 170-174 (2009-12-29)
Charcot-Marie-Tooth disease type 2C (CMT2C) is an autosomal dominant neuropathy characterized by limb, diaphragm and laryngeal muscle weakness. Two unrelated families with CMT2C showed significant linkage to chromosome 12q24.11. We sequenced all genes in this region and identified two heterozygous
Chou-Long Huang
Journal of the American Society of Nephrology : JASN, 15(7), 1690-1699 (2004-06-24)
ABSTRACT. The transient receptor potential (TRP) superfamily of proteins is cation-selective ion channels with six predicted transmembrane segments and intracellularly localized amino and carboxyl termini. Members of the TRP superfamily are identified on the basis of amino acid sequence and
Lyudmyla Borysova et al.
Nature protocols, 16(10), 4650-4675 (2021-08-18)
Ca2+ handling within cardiac myocytes underpins coordinated contractile function within the beating heart. This protocol enables high spatial and temporal Ca2+ imaging of ex vivo multicellular myocardial strips. The endocardial surface is retained, and strips of 150-300-µm thickness are dissected
Ashwini Saxena et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 307(8), R945-R955 (2014-08-01)
Transient receptor potential vanilloid family type 4 (TRPV4) channels are expressed in central neuroendocrine neurons and have been shown to be polymodal in other systems. We previously reported that in the rodent, a model of dilutional hyponatremia associated with hepatic
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