T8941

L-Tryptophan

99.0-101.0%, suitable for cell culture, BioXtra, non-animal source

• Synonym(s): (S)-2-Amino-3-(3-indolyl)propionic acid, L-α-Amino-3-indolepropionic acid
• Empirical Formula (Hill Notation): C₁₁H₁₂N₂O₂
• CAS Number: 73-22-3
• Molecular Weight: 204.23
• Beilstein: 86197
• EC Number: 200-795-6
• MDL number: MFCD00064340
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24900575
• NACRES: NA.26

Properties

• product name: L-Tryptophan, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%
• biological source: non-animal source
• Quality Level: 300
• Agency: USP/NF; meets EP testing specifications; meets JP testing specifications; meets USP testing specifications
• product line: BioXtra
• Assay: 99.0-101.0%
• form: powder
• quality: meets EP, JP, USP testing specifications
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• color: white to yellow
• mp: 280-285 °C (dec.) (lit.)
• solubility: 1 M HCl: 10 mg/mL
• application(s): pharmaceutical (small molecule)
• SMILES string: N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
• InChI: 1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1
• InChI key: QIVBCDIJIAJPQS-VIFPVBQESA-N

Description

Application

L-Tryptophan has been used in PreC media preparation and in cell culture.

Biochem/physiol Actions

Tryptophan (Trp) is one of the functional amino acids that is associated with growth, reproduction, maintenance and immunity. Increased Trp availability is necessary for the regulation of mood, cognition and behaviour. It is hypothesised that L-Trp might be useful in inducing sleep in healthy adults against the normal circadian rhythm. Trp uptake by the brain depends on the plasma ratio of Trp to all of the other LNAAs (large neutral amino acids). Higher the Trp:LNAAs ratio, greater is the Trp uptake.

Other Notes

Amino acid precursor of serotonin and melatonin

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves