Skip to Content
Merck
All Photos(1)

Key Documents

SML2173

Sigma-Aldrich

NS3861

≥98% (HPLC)

Synonym(s):

3-(3-Bromo-2-thienyl)-8-methyl-8-azabicyclo[3.2.1]oct-2-ene, NS 3861

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C12H14BrNS
CAS Number:
Molecular Weight:
284.22
UNSPSC Code:
12352200
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

BrC1=C(SC=C1)C2=CC(N3C)CCC3C2

Biochem/physiol Actions

NS3861 is a neuronal nicotinic receptor agonist that selectively activates α3 containing nAChRs and it displays higher efficacy at the α3β2 receptor compared with the α3β4 receptor. NS3861 does not activate α4 containing receptors. NS3861 was reported to reverse chronic opioid-induced constipation in vivo.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service