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Key Documents

SAB5300042

Sigma-Aldrich

Monoclonal Anti-PAR1 antibody produced in mouse

clone 6A7H10, ascites fluid

Synonym(s):

D15S227E, PAR1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

6A7H10, monoclonal

species reactivity

human

technique(s)

direct ELISA: 1:10,000
western blot: 1:500-1:2,000

isotype

IgG1

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PAR1(145624)

Immunogen

Purified recombinant fragment of PAR1 expressed in E.coli.
Mouse monoclonal antibody raised against PAR1

Physical form

Ascitic fluid containing 0.03% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Zhong-Hua Fu et al.
Molecular medicine reports, 16(5), 7375-7381 (2017-09-26)
The aim of the present study was to determine the effects of early anticoagulation treatment on severe burns complicated by inhalation injury in a rabbit model. Under anesthetization, an electrical burns instrument (100˚C) was used to scald the backs of
Daniela Brünnert et al.
Journal of reproductive immunology, 132, 35-41 (2019-03-25)
Extravillous trophoblast (EVT) migration and invasion is the crucial step for normal placental development. IL-11 is a cytokine regulating cell migration and invasion in cells and is a critical factor for successful implantation of an embryo. Higher expression of thrombin
Haiyan Huang et al.
Biochemical and biophysical research communications, 452(3), 708-714 (2014-09-10)
Benzo(a)pyrene (BaP) is a known carcinogen cytotoxic which can trigger extensive cellular responses. Many evidences suggest that inhibitors of poly(ADP-ribose) glycohydrolase (PARG) are potent anticancer drug candidates. However, the role of PARG in BaP carcinogenesis is less understood. Here we
Tsugunobu Andoh et al.
Pharmacological reports : PR, 66(4), 699-703 (2014-06-21)
Proteinase-activated receptor-2 (PAR2) is involved in dermatophyte-induced scratching and leukotriene B4 (LTB4) release from keratinocytes. We investigated whether PAR2-mediated LTB4 production is involved in dermatophyte-induced scratching. Dermatophyte extract was injected intradermally and scratching was observed in mice. LTB4 was determined
Fei Wang et al.
American journal of physiology. Renal physiology, 307(1), F25-F32 (2014-04-18)
(Pro)renin receptor (PRR) is predominantly expressed in the distal nephron where it is activated by angiotensin II (ANG II), resulting in increased renin activity in the renal medulla thereby amplifying the de novo generation and action of local ANG II.
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