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P1504

Sigma-Aldrich

TWEEN® 40

viscous liquid

Synonym(s):

Polyoxyethylenesorbitan monopalmitate

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About This Item

CAS Number:
9005-66-7
MDL number:
MFCD00165345
UNSPSC Code:
12161900
NACRES:
NA.25

description

non-ionic

Assay

~90.0% (GC)

form

viscous liquid

mol wt

estimated mol wt 1277

composition

Palmitic acid, ~90% (balance primarily stearic acid)

technique(s)

DNA extraction: suitable
RNA extraction: suitable
cell culture | mammalian: suitable
protein purification: suitable

CMC

0.027 (20-25°C)

HLB

15.6

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

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General description

Polyoxyethylenesorbitan monopalmitate, or TWEEN 40, is a non-ionic detergent.

Application

Non-ionic detergent used for cell lysis, nuclei isolation and cell fractionation.
Polyoxyethylenesorbitan monopalmitate, or TWEEN 40, has been used in a study to assess the determination of iodide in urine based on a chemiluminescence system. It has also been used in a study to investigate the delivery of astaxanthin and canthaxanthin to HepG2 cells.

Legal Information

TWEEN is a registered trademark of Croda International PLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Christine Boesch-Saadatmandi et al.
Cytotechnology, 63(1), 89-97 (2010-12-15)
The present investigation aimed to compare fetal calf serum (FCS) and Tween 40 with the commonly employed tetrahydrofuran (THF) with respect to cytotoxicity, stability of the solubilized carotenoids, and uptake and accumulation of the xanthophylls astaxanthin (AX) and canthaxanthin (CX)
Determination of iodide in urine based on chemiluminescence system of cerium (IV)-tween 40-iodide
Li and Xie
Journal of Luminescence, 132, 5-5 (2012)
F Podlogar et al.
International journal of pharmaceutics, 276(1-2), 115-128 (2004-04-29)
Pharmaceutically usable microemulsion systems were prepared from water and isopropyl myristate with a constant amount of Tween 40 and Imwitor 308 at a mass ratio of 1. Their type and structure were examined by measuring density and surface tension, and
F Podlogar et al.
International journal of pharmaceutics, 302(1-2), 68-77 (2005-08-16)
Microemulsions are a promising vehicle for administrating drugs. In order to lay the basis for predicting drug release under in vivo conditions, where the microemulsion composition is continuously varying, we have studied the release of ketoprofene as a model drug
Jongpill Kim et al.
Applied microbiology and biotechnology, 91(1), 143-151 (2011-04-20)
Glutamate overproduction by Corynebacterium glutamicum is triggered by treatment with penicillin or Tween 40 and is accompanied by a decrease in 2-oxoglutarate dehydrogenase complex (ODHC) activity. We have reported that de novo synthesis of OdhI, which inhibits ODHC activity by
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