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F6937

Sigma-Aldrich

Fluoroshield with 1,4-Diazabicyclo[2.2.2]octane

pH range 8.0-8.4, Aqueous mounting medium

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.47

Quality Level

form

liquid

technique(s)

immunofluorescence: suitable

pH range

8.0-8.4

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

General description

Fluoroshield with 1,4-Diazabicyclo[2.2.2]octane is an aqueous mounting medium for preserving the fluorescence of tissue and cell smears.

Application

Fluoroshield with 1,4-Diazabicyclo[2.2.2]octane prevents rapid photobleaching of FITC, Texas Red®, AMCA, 488, Alexa Fluor 594, Cy® dyes, and tetramethylrhodamine.

Principle

Fluoroshield with 1,4-Diazabicyclo[2.2.2]octane mounting medium is fortified with 1,4-Diazabicyclo[2.2.2]octane (a generic version of DABCO®), an anti-fade reagent used to retard photobleaching of fluorescein and other fluorescent dyes.

Legal Information

ALEXA FLUOR is a trademark of Life Technologies
Cy is a registered trademark of Cytiva
DABCO is a registered trademark of Air Products & Chemicals, Inc.
FluoroShield is a trademark of ImmunoBioScience Corp.
Texas Red is a registered trademark of Life Technologies

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Description
Pricing

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Dam. 1

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Nour W Al Haj Baddar et al.
Developmental dynamics : an official publication of the American Association of Anatomists, 248(2), 189-196 (2018-12-21)
Among vertebrates, salamanders are unparalleled in their ability to regenerate appendages throughput life. However, little is known about early signals that initiate regeneration in salamanders. Ambystoma mexicanum embryos were administered tail amputations to investigate the timing of reactive oxygen species
Ibtisam A Abbas Al-Darkazly et al.
IEEE journal of translational engineering in health and medicine, 8, 4100113-4100113 (2020-01-31)
Objective: investigation of the extra-low-frequency (ELF) stimulation effect on blood-cell proteins, that causes variation in its electrostatic-state. A hypothesis that this results in the conformational change in the blood-cell proteins which could enhance immune activity is explored. Since HIV-1 and
Morphological changes of cortical and hippocampal neurons after treatment with VEGF and bevacizumab.
Latzer P, et al.
CNS Neuroscience & Therapeutics, 22(6), 440-450 (2016)
Mariana L Casalia et al.
Annals of neurology, 82(4), 530-542 (2017-08-24)
A significant proportion of the more than 50 million people worldwide currently suffering with epilepsy are resistant to antiepileptic drugs (AEDs). As an alternative to AEDs, novel therapies based on cell transplantation offer an opportunity for long-lasting modification of epileptic
Kevin Glaesel et al.
International journal of molecular sciences, 21(11) (2020-06-03)
The wide-ranging influence of vascular endothelial growth factor (VEGF) within the central (CNS) and peripheral nervous system (PNS), for example through effects on axonal growth or neuronal cell survival, is mainly mediated by VEGF receptor 2 (VEGFR-2). However, the regulation

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