B4894

Benzyl 2-acetamido-2-deoxy-α-D-galactopyranoside hydrate

O-glycosylation inhibitor, ≥97% (TLC)

• Synonym(s): Benzyl-α-GalNAc, α-D-GalNAc-1→OCH₂Ph, Benzyl N-acetyl-α-D-galactosaminide, GalNAc α-O-benzyl, GalNAc-O-bn
• Empirical Formula (Hill Notation): C₁₅H₂₁NO₆ · xH₂O
• CAS Number: 3554-93-6
• Molecular Weight: 311.33 (anhydrous basis)
• MDL number: MFCD00057920
• UNSPSC Code: 12352201
• PubChem Substance ID: 24891802
• NACRES: NA.25

Properties

• Quality Level: 100
• Assay: ≥97% (TLC)
• form: powder
• color: white to off-white
• mp: 204-208 °C
• solubility: methanol: soluble 10 mg/mL, clear
• storage temp.: −20°C
• SMILES string: CC(N[C@H]([C@H]([C@H]1O)O)[C@H](O[C@@H]1CO)OCC2=CC=CC=C2)=O
• InChI: InChI=1S/C15H21NO6/c1-9(18)16-12-14(20)13(19)11(7-17)22-15(12)21-8-10-5-3-2-4-6-10/h2-6,11-15,17,19-20H,7-8H2,1H3,(H,16,18)/t11-,12-,13+,14-,15+/m1/s1
• InChI key: SKOZFDIGKDPQBO-QMIVOQANSA-N

Description

Biochem/physiol Actions

Benzyl-N-acetyl-α-galactosaminide inhibits glycosyltransferase incorporation of glucosamine into O-glycans. Suppresses mucin biosynthesis and inhibits MUC1 expression in breast cancer cell line MDF-7.

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves