B3295

Biotinamidohexanoyl-6-aminohexanoic acid N-hydroxysuccinimide ester

≥95% (TLC), powder

• Synonym(s): 6-(Biotinamidocaproylamido)caproic acid N-hydroxysuccinimide ester, Biotin-X-X-NHS, N-Succinimidyl N-[6-(biotinylamino)caproyl]-6-aminocaproate
• Empirical Formula (Hill Notation): C₂₆H₄₁N₅O₇S
• CAS Number: 89889-52-1
• Molecular Weight: 567.70
• Beilstein: 8377428
• MDL number: MFCD00467154
• UNSPSC Code: 12352106
• PubChem Substance ID: 24891708
• NACRES: NC.07

Properties

• Assay: ≥95% (TLC)
• form: powder
• solubility: DMF: 25 mg/mL
• storage temp.: −20°C
• SMILES string: [H][C@]12CS[C@@H](CCCCC(=O)NCCCCCC(=O)NCCCCCC(=O)ON3C(=O)CCC3=O)[C@@]1([H])NC(=O)N2
• InChI: 1S/C26H41N5O7S/c32-20(27-16-8-2-4-12-24(36)38-31-22(34)13-14-23(31)35)10-3-1-7-15-28-21(33)11-6-5-9-19-25-18(17-39-19)29-26(37)30-25/h18-19,25H,1-17H2,(H,27,32)(H,28,33)(H2,29,30,37)/t18-,19-,25-/m0/s1
• InChI key: ATYCFNRXENKXSE-MHPIHPPYSA-N

Description

Application

Biotinamidohexanoyl-6-aminohexanoic acid N-hydroxysuccinimide ester has been used in human IgM biotinylation.

Biotinylation reagent incorporating an extended 14-atom spacer can reduce steric hindrance in binding avidin or streptavidin to some biotinylated compounds and increase sensitivity for detection. Typically coupled to primary amine in the pH range 6.5-8.5.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable