32053
Bronopol
PESTANAL®, analytical standard
Synonym(s):
2-Bromo-2-nitro-1,3-propanediol, BNPD, BNPK, Bronopol
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About This Item
Linear Formula:
HOCH2C(Br)(NO2)CH2OH
CAS Number:
Molecular Weight:
199.99
Beilstein:
1705868
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
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grade
analytical standard
Quality Level
product line
PESTANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
130-133 °C (lit.)
application(s)
agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care
format
neat
SMILES string
OCC(Br)(CO)[N+]([O-])=O
InChI
1S/C3H6BrNO4/c4-3(1-6,2-7)5(8)9/h6-7H,1-2H2
InChI key
LVDKZNITIUWNER-UHFFFAOYSA-N
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General description
Bronopol is a broad-spectrum antibacterial agent. It is mostly used as a preservative in cosmetic, toiletry etc. It is also used in aerosol formulations.1
Application
Bronopol has been used as reference standard in ultra performance liquid chromatography (UPLC) coupled to inductively coupled plasma mass spectrometry (UPLC-ICP-MS) method for determination of bromine containing preservatives from cosmetic products.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
4.1B - Flammable solid hazardous materials
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Hyphenation of ultra performance liquid chromatography (UPLC) with inductively coupled plasma mass spectrometry (ICP-MS) for fast analysis of bromine containing preservatives.
Bendahl L et.al.
Journal of Pharmaceutical and Biomedical Analysis, 40(3), 648-652 (2006)
František Bílek et al.
Colloids and surfaces. B, Biointerfaces, 88(1), 440-447 (2011-08-06)
Low-density polyethylene (LDPE) samples were treated in air plasma discharge, coated by polyallyamine brush thought copolymeric grafting surface-from reaction and deposited four common antibacterial agents (benzalkonium chloride, bronopol, chlorhexidine and triclosan) to gain material with active antibacterial properties. Surface characteristics
M Matczuk et al.
International journal of cosmetic science, 34(5), 451-457 (2012-05-23)
Bronopol (2-bromo-2-nitropropane-1,3-diol) is used as preservative in cosmetic industry. Its main role in commercial products consists in protection of the cosmetic composition stability by inhibiting the development of micro-organisms. Unfortunately, preservatives can also undergo the degradation processes. The aim of
Lars Bendahl et al.
Journal of pharmaceutical and biomedical analysis, 40(3), 648-652 (2006-01-19)
Ultra performance liquid chromatography (UPLC) was coupled to inductively coupled plasma mass spectrometry (ICP-MS) for fast analysis of three bromine-containing preservatives, monitoring the 79Br and 81Br isotopes simultaneously. Due to the efficiency of the 1.7 microm column packing material, the
D Sierra et al.
Journal of dairy science, 92(10), 4841-4845 (2009-09-19)
This study was designed to evaluate the effects of different storage conditions on total bacterial count (TBC) determinations made in goat bulk tank milk using an automated flow cytometry method. The storage conditions tested were storage temperature (refrigeration at 4
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