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Key Documents

MAB356

Sigma-Aldrich

Anti-Substance P Antibody, pain, clone NC1

culture supernatant, clone NC1, Chemicon®

Synonym(s):

Anti-Hs.2563, Anti-NK2, Anti-NKNA, Anti-NPK, Anti-TAC2

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rat

Quality Level

100

antibody form

culture supernatant

antibody product type

primary antibodies

clone

NC1, monoclonal

species reactivity

human

species reactivity (predicted by homology)

mammals

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

isotype

IgG2a

NCBI accession no.

NM_003182.1
NM_013996.1
NM_013997.1
NM_013998.1

UniProt accession no.

P20366

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... TAC1(6863)

Specificity

Reacts with COOH-terminal end of Substance P. No cross-reactivity to Leu- or Met- enkephalin, somatostatin or beta-endorphin. Eledoisin 5%.

Immunogen

Substance P conjugated to BSA.

Application

1:100 - 1:200 by immunohistochemistry on human brain.

Optimal working dilutions must be determined by end user.
Detect Substance P using this Anti-Substance P Antibody, pain, clone NC1 validated for use in IH.

Physical form

Lyophilized Supernatant, preservative free.

Storage and Stability

Lyophilized antibody can be kept at 2-8°C for up to 3 months and should be kept at -20°C for long term storage. Reconstitute with 100μL sterile DI water. Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ding, S; Chi, MM; Scull, BP; Rigby, R; Schwerbrock, NM; Magness, S; Jobin, C; Lund, PK
Testing null
Sacro-lumbar intersegmental spinal reflex in autonomic pathways mediating female sexual function.
Shi Yong Yuan,Ian L Gibbins,Vladimir P Zagorodnyuk,Judy L Morris
Journal of Sexual Medicine null
Ultrastructure and distribution of substance P-immunoreactive sensory collaterals in the guinea pig prevertebral sympathetic ganglia.
Matthews, M R, et al.
The Journal of Comparative Neurology, 258, 28-51 (1987)
Hypoalgesia in mice with a targeted deletion of the tachykinin 1 gene.
Zimmer, A; Zimmer, AM; Baffi, J; Usdin, T; Reynolds, K; Konig, M; Palkovits, M; Mezey, E
Proceedings of the National Academy of Sciences of the USA null
Andrew P Ray et al.
Pharmacology, biochemistry, and behavior, 94(1), 211-218 (2009-08-25)
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