AB5566
Anti-Capsaicin Receptor Antibody, CT
serum, Chemicon®
Synonym(s):
Vanilloid Receptor 1, VR1
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
guinea pig
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... TRPV1(7442)
Specificity
Recognizes Capsaicin Receptor (Vanilloid Receptor 1, VR1).
Immunogen
A 22 amino acid peptide corresponding to the C-terminus of the rat Capsaicin Receptor protein (Catalog number AG298).
Application
Anti-Capsaicin Receptor Antibody, C-terminus detects level of Capsaicin Receptor & has been published & validated for use in IH.
Immunohistochemistry: 1:1,000. The antibody reacts well with tissue from the rat dorsal root ganglia.
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Physical form
Serum. Liquid. Contains less than 0.02% sodium azide.
Analysis Note
Control
Immunogen peptide (catalog number AG298) is available for preadsorbtion control studies.
Immunogen peptide (catalog number AG298) is available for preadsorbtion control studies.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Activation of vanilloid receptor type I in the endoplasmic reticulum fails to activate store-operated Ca2+ entry
Wisnoskey, B. J. et al.
The Biochemical Journal, 372(Pt 2), 517-528 (2003)
S-Q He et al.
Neuroscience, 261, 43-51 (2014-01-01)
Mas-related G-protein-coupled receptor subtype C (MrgC) may play an important role in pain sensation. However, the distribution of MrgC receptors in different subpopulations of rodent dorsal root ganglion (DRG) neurons has not been clearly demonstrated owing to a lack of
Yumi Matsushita et al.
The Journal of veterinary medical science, 83(10), 1570-1581 (2021-09-03)
The activation of α2 adrenergic receptors contributes to analgesia not only in the central nervous system but also in the peripheral nervous system. We reported that noradrenaline inhibits the activity of transient receptor potential vanilloid 1 (TRPV1) evoked by capsaicin
Diane M Bogdan et al.
Scientific reports, 12(1), 9241-9241 (2022-06-03)
The endocannabinoid anandamide (AEA) produces antinociceptive effects by activating cannabinoid receptor 1 (CB1). However, AEA also serves as an agonist at transient receptor potential vanilloid receptor 1 (TRPV1) in nociceptive sensory neurons, which may exacerbate pain. This potential functional duality
Intrathecal injection of TRPV1 shRNA leads to increases in blood pressure in rats.
Yu, SQ; Wang, DH
Acta Physiologica (Oxford, England) null
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