561306

P-Selectin, Human, Recombinant, CHO Cells

• Synonym(s): CD62P, GMP-140, LECAM-3, PADGEM
• UNSPSC Code: 12352202

Properties

• recombinant: expressed in CHO cells
• Quality Level: 100
• Assay: ≥95% (SDS-PAGE)
• form: lyophilized
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• impurities: <1.5 EU/μg Endotoxins (EU/μg of P-Selectin)
• shipped in: wet ice
• storage temp.: −20°C

Description

General description

Recombinant, human P-selectin consisting of 730 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is expressed on activated platelets and endothelial cells. A specific interaction between P-selectin and P-selectin glycoprotein ligand-1, present on numerous cell types, promotes adhesion and acts along with L-selectin in establishing an initial interaction between circulating leukocytes and the endothelium.

Biochem/physiol Actions

Shown to bind to P-selectin ligands on U937 cells.

Warning

Toxicity: Standard Handling (A)

Physical form

Lyophilized from Dulbecco’s D-PBS (containing calcium and magnesium), 1% sorbitol.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Reconstitute at 1 mg/ml in sterile H₂O.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1