860602P

D-ribo-phytosphingosine (C17 base)

Avanti Polar Lipids 860602P, powder

• Synonym(s): 4-hydroxysphinganine (C17 base)
• Empirical Formula (Hill Notation): C₁₇H₃₇NO₃
• CAS Number: 40289-37-0
• Molecular Weight: 303.48
• UNSPSC Code: 12352211

Properties

• form: powder
• packaging: pkg of 1 × 10 mg (860602P-10mg); pkg of 1 × 5 mg (860602P-5mg)
• manufacturer/tradename: Avanti Polar Lipids 860602P
• lipid type: sphingolipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O[C@]([H])(CCCCCCCCCCCCC)[C@](O)([H])[C@](N)([H])CO

Description

General description

D-ribo-phytosphingosine (C17 base), also known as 4D-hydroxysphinganine or PHS, is widely found in membranes of fungi, plants, bacteria, marine organisms and mammalian tissues.

Application

D-ribo-phytosphingosine (C17 base) has been used as a standard for the quantification of total plant long-chain bases (LCB) by gas chromatography-mass spectrometry (GC-MS).

Biochem/physiol Actions

D-ribo-phytosphingosine helps in maintaining the structural integrity of membrane. It also controls cellular growth and mediates the heat stress response of yeast. In addition, PHS acts as a precursor for synthesis of various key lipid mediators including PHS 1-phosphate, inositol phosphorylceramide and KRN7000 (α-anomer of galactosylceramide). This phospholipid also has an ability to stimulate keratinocyte differentiation. Therefore, PHS is used as an active constituent in cosmetic formulations.

Packaging

5 mL Amber Glass Screw Cap Vial (860602P-10mg)

5 mL Amber Glass Screw Cap Vial (860602P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3