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900860

Sigma-Aldrich

3-Amino-5-ethynylbenzenesulfonyl fluoride

≥95%

Synonym(s):

Amino sulfonyl fluoride alkyne, Probe building block

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About This Item

Empirical Formula (Hill Notation):
C8H6FNO2S
CAS Number:
Molecular Weight:
199.20
UNSPSC Code:
12352200
NACRES:
NA.22

Assay

≥95%

form

powder or crystals

storage temp.

−20°C

SMILES string

NC1=CC(S(=O)(F)=O)=CC(C#C)=C1

Application

3-Amino-5-ethynylbenzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and amine synthetic handle. When appended to a ligand or pharmacophore through its amine linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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