524433

N-Benzylcinchonidinium bromide

97%

• Empirical Formula (Hill Notation): C₂₆H₂₉BrN₂O
• CAS Number: 118089-84-2
• Molecular Weight: 465.43
• MDL number: MFCD02093777
• UNSPSC Code: 12352101
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• optical activity: [α]20/D −138°, c = 1 in chloroform
• mp: 190 °C (dec.) (lit.)
• InChI key: UUVFTQCFSNVLGV-SPTWEYDNSA-M

Description

General description

N-Benzylcinchonidinium bromide is a chiral phase-transfer catalyst (PTC).

Application

N-Benzylcinchonidinium bromide (BCDBr) can be used:

• To prepare various 4-(bromomethyl)benzenesulfonamides, which are employed as catalysts for asymmetric benzylation reactions.
• As a phase transfer catalyst in the synthesis of organogelators via Michael addition reaction.
• To catalyze the enantioselective alkylation of tert-butyl glycinate-benzophenone Schiff base furnishing the corresponding chiral α-amino acid.
• To resolve symmetric biaryldiols via formation of inclusion complex with diols.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves