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382310

Sigma-Aldrich

Didecyldimethylammonium bromide

98%

Synonym(s):

DDAB

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About This Item

Linear Formula:
[CH3(CH2)9]2N(CH3)2Br
CAS Number:
Molecular Weight:
406.53
Beilstein:
6492993
EC Number:
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

mp

149-151 °C (lit.)

SMILES string

[Br-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC

InChI

1S/C22H48N.BrH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1

InChI key

UMGXUWVIJIQANV-UHFFFAOYSA-M

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Application

Didecyldimethylammonium bromide (DDAB) is commonly used as a surfactant and a phase transfer catalyst. It is also used in the preparation of hydrophobic ammonium-based ionic liquid.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Nucleic acids research, 37(15), 5197-5207 (2009-06-30)
Despite considerable interest and investigations on cationic lipid-DNA complexes, reports on lipid-RNA interaction are very limited. In contrast to lipid-DNA complexes where lipid binding induces partial B to A and B to C conformational changes, lipid-tRNA complexation preserves tRNA folded
C Carbone et al.
Colloids and surfaces. B, Biointerfaces, 167, 337-344 (2018-04-24)
In this work, we aimed at developing an improved topical SLN formulation combining itraconazole delivery with a coating layer of didodecyldimethylammonium bromide, thus repurposing the drug effectiveness by synergistic skin anticancer effectiveness. In order to obtain a stable SLN formulation
Jie Qu et al.
Drug delivery, 23(9), 3408-3416 (2016-05-18)
Glioblastoma is a malignant brain tumor originating in the central nervous system. Successfully therapy of this disease required the efficient delivery of therapeutic agents to the tumor cells and tissues. Delivery of anticancer drugs using novel nanocarriers is promising in
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