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259268

Sigma-Aldrich

Hexaethylene glycol

97%, average MN 300

Synonym(s):

Polyethylene glycol, 3,6,9,12,15-Pentaoxaheptadecane-1,17-diol

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About This Item

Linear Formula:
H(OCH2CH2)6OH
CAS Number:
2615-15-8
Molecular Weight:
282.33
Beilstein:
1638281
EC Number:
220-045-1
MDL number:
MFCD00002877
UNSPSC Code:
12162002
PubChem Substance ID:
24855697
NACRES:
NA.23

product name

Hexaethylene glycol, 97%

Quality Level

200

Assay

97%

form

liquid

mol wt

average Mn 300

refractive index

n20/D 1.465 (lit.)

bp

217 °C/4 mmHg (lit.)

mp

5-7 °C (lit.)

density

1.127 g/mL at 25 °C (lit.)

Ω-end

hydroxyl

α-end

hydroxyl

SMILES string

OCCOCCOCCOCCOCCOCCO

InChI

1S/C12H26O7/c13-1-3-15-5-7-17-9-11-19-12-10-18-8-6-16-4-2-14/h13-14H,1-12H2

InChI key

IIRDTKBZINWQAW-UHFFFAOYSA-N

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Related Categories

Application

Substrate employed in the synthesis of binaphthol-based macrocyclic ethers using intramolecular oxidative coupling with CuCl(OH)-TMEDA.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

No data available

Flash Point(C)

No data available

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
WXBD5884V
WXBD4515V
WXBD4075V
WXBD3488V
WXBD3039V

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Tetrahedron Letters, 47, 8563-8563 (2006)
A Carmon et al.
BioTechniques, 32(2), 410-410 (2002-02-19)
During the solid-phase PCR (SP-PCR), DNA oligonucleotides complementary to a soluble template and immobilized on a surface are extended in situ. Although primarily used for pathogen detection, SP-PCR has the potential for much broader application, including disease diagnostics, genotyping, and
K R Fox et al.
Biochemistry, 39(22), 6714-6725 (2000-06-01)
We have used DNase I footprinting to examine the binding of five different 17-mer oligonucleotides to a 53-base oligopurine tract containing four pyrimidine interruptions. Although all the expected triplexes formed with high affinity (K(d) approximately 10-50 nM), one oligonucleotide produced
Monique J Bruining et al.
Biomaterials, 23(4), 1213-1219 (2002-01-17)
A well-known complication in corneal repair surgery is (recurrent) rejection of donor corneal tissue. particularly in patients suffering from an auto-immune disease such as rheumatoid arthritis. Down-regulation of their immune system, by means of drugs, is necessary in order to
Dorota Bartczak et al.
Nanoscale, 4(15), 4470-4472 (2012-06-30)
We present the exocytosis profile of two types of peptide-coated nanoparticles, which have similar charge and size but different functionality. While one kind of particles appears to progressively exocytose, the other one has a more complex profile, suggesting that some
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Articles

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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