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199656

Sigma-Aldrich

Sudan II

Dye content 90 %

Synonym(s):

1-(2,4-Xylylazo)-2-naphthol, Solvent Orange 7

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About This Item

Empirical Formula (Hill Notation):
C18H16N2O
CAS Number:
Molecular Weight:
276.33
Colour Index Number:
12140
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

form

powder

composition

Dye content, 90%

mp

156-158 °C (lit.)

solubility

chloroform: 10 mg/mL

λmax

493 nm
604 nm (2nd)

ε (extinction coefficient)

≥14000 at 491-497 nm in methanol at 0.005 g/L
≥9000 at 419-425 nm in methanol at 0.005 g/L

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Cc1ccc(\N=N\c2c(O)ccc3ccccc23)c(C)c1

InChI

1S/C18H16N2O/c1-12-7-9-16(13(2)11-12)19-20-18-15-6-4-3-5-14(15)8-10-17(18)21/h3-11,21H,1-2H3/b20-19+

InChI key

JBTHDAVBDKKSRW-FMQUCBEESA-N

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Application

Sudan II has been used to determine its presence in commercial spices such as hot chilli food samples (LC–ESI–MS/MS).

Biochem/physiol Actions

Sudan II is a fat-soluble synthetic colorant and it belongs to the group of azo compounds. It is classified by the international agency for research on cancer (IARC) as category 3 carcinogens because it has an ability to cause certain forms of liver and bladder cancer in animals.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

448.9 °F - closed cup

Flash Point(C)

231.6 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Determination of banned Sudan dyes in chili powder by capillary electrophoresis
Mejia E
Food Chemistry, 102, 1027-1033 (2007)
Simultaneous determination of water-soluble and fat-soluble synthetic colorants in foodstuff by high-performance liquid chromatography-diode array detection-electrospray mass spectrometry.
Ma M
Journal of Chromatography A, 1103, 170-176 (2006)
Determining the adulteration of spices with Sudan I-II-II-IV dyes by UV-visible spectroscopy and multivariate classification techniques.
Di Anibal CV
Talanta, 79, 887-892 (2009)
Ali A Ensafi et al.
Talanta, 88, 244-251 (2012-01-24)
A simple and inexpensive methodology was used to develop a novel electrochemical sensor for the determination of Sudan II. The interaction of Sudan II with salmon sperm ds-DNA on the surface of salmon sperm ds-DNA-modified pencil graphite electrode (PGE) and
Ting Xu et al.
Analytical biochemistry, 405(1), 41-49 (2010-06-05)
To obtain antibodies to develop an enzyme-linked immunosorbent assay (ELISA) for the analysis of Sudan red I, haptens were designed and synthesized via four different strategies: (i) attachment of a spacer at the para position of the benzene ring, (ii)

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