123323

Quinazoline

99%

• Synonym(s): 1,3-Benzodiazine, Benzopyrimidine
• Empirical Formula (Hill Notation): C₈H₆N₂
• CAS Number: 253-82-7
• Molecular Weight: 130.15
• Beilstein: 109370
• EC Number: 205-965-3
• MDL number: MFCD00006712
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847559
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 99%
• form: solid
• bp: 243 °C (lit.)
• mp: 46-48 °C (lit.)
• solubility: H₂O: freely soluble; organic solvents: soluble
• SMILES string: c1ccc2ncncc2c1
• InChI: 1S/C8H6N2/c1-2-4-8-7(3-1)5-9-6-10-8/h1-6H
• InChI key: JWVCLYRUEFBMGU-UHFFFAOYSA-N

Description

General description

Quinazolines has applications in medicinal chemistry due to their antibacterial, antifungal, anticonvulsant, anti-inflammatory and antitumor activities. It is the basic structural unit of pharmaceuticals and plays an important role in modern synthesis of antitumor drugs.

Application

Quinazoline was used to study the electrochemical behaviour of quinazoline using modern polarographic and voltammetric methods.

Biochem/physiol Actions

Genotoxicity of quinazoline was established by bacterial SOS Chromotest (Escherichia Coli).

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 222.8 °F - closed cup
• Flash Point(C): 106 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves