V900422

Folic acid

Vetec^™, reagent grade, ≥97%

• Synonim(y): PteGlu, Pteroyl-L-glutamic acid, Vitamin M
• Wzór empiryczny (zapis Hilla): C₁₉H₁₉N₇O₆
• Numer CAS: 59-30-3
• Masa cząsteczkowa: 441.40
• Beilstein: 100781
• Numer WE: 200-419-0
• Numer MDL: MFCD00079305
• Kod UNSPSC: 12352106
• Identyfikator substancji w PubChem: 329829830

Właściwości

• klasa czystości: reagent grade
• linia produktu: Vetec^™
• Próba: ≥97%
• Postać: powder
• metody: HPLC: suitable
• kolor: yellow to orange
• mp: >285 °C
• ciąg SMILES: NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O
• InChI: 1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
• Klucz InChI: OVBPIULPVIDEAO-LBPRGKRZSA-N

Opis

Opis ogólny

Folic acid belongs to vitamin B group and is also called as vitamin B₉ or folate. It is present as 5-methyltetrahydrofolate in humans. Grains, fruits and vegetables are dietary sources of folate. Pteroylmonoglutamate is a synthetic folate which comprises single glutamate and exists in the oxidized state.

Działania biochem./fizjol.

Folic acid is essential for cell growth, brain functioning and plays a key role on serine production from glycine. It also coordinates with vitamin B₁₂ in maintaining iron levels. Deficiency of folate is implicated in megaloblastic anemia. Folic acid aids in the repair and synthesis of DNA. Dietary supplementation and fortification of folate in foods is recommended for pregnant women especially in the first trimester to avoid congenital malformation and neural tube defects (NTDs). However, folate fortification may also impose a moderate risk of developing prostate cancer. Supplementation of folate to colon cancer cells diminishes iron levels and impairs the cell division.

Informacje prawne

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1