TLR9
toll-like receptor 9
Synonimy:
CD289
Gatunek:
Human TLR9 (54106), Mouse Tlr9 (81897), Rat Tlr9 (338457), Zebrafish tlr9 (403128), domestic cat TLR9 (493839), Horse TLR9 (100009693), dog TLR9 (403502), cow TLR9 (282602), sheep TLR9 (494547), Goat TLR9 (100860819)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(54106) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Jul 2008]
- Mouse(81897) toll-like receptor 9
- Rat(338457) toll-like receptor 9
- Zebrafish(403128) toll-like receptor 9
- domestic cat(493839) toll-like receptor 9
- Horse(100009693) toll-like receptor 9
- dog(403502) toll-like receptor 9
- cow(282602) toll-like receptor 9
- sheep(494547) toll-like receptor 9
- Goat(100860819) toll-like receptor 9
- naked mole-rat(101715478) toll-like receptor 9
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Small Molecule - Antagonist
Numer produktu
Opis
Gatunek
2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
Hydroxychloroquine Sulfate, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-TLR9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-TLR9, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, goat, horse, human, pig, sheep
Zastosowanie
western blot
ANTI-TLR9 antibody produced in mouse, clone 2G3, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
western blot
ANTI-TLR9 antibody produced in mouse, clone 3B7, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
western blot
ANTI-TLR9 antibody produced in mouse, clone 2C3, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
western blot