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Merck

NCOR2

nuclear receptor corepressor 2

Synonimy:
CTG26, N-CoR2, SMAP270, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC, TRAC-1, TRAC1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(9612) Summary: This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]
  • Mouse(20602) nuclear receptor co-repressor 2
  • Rat(360801) nuclear receptor co-repressor 2
  • Zebrafish(561503) nuclear receptor co-repressor 2
  • chicken(416815) nuclear receptor corepressor 2
  • cow(538549) nuclear receptor corepressor 2
  • Horse(100059253) nuclear receptor corepressor 2
  • domestic cat(101083973) nuclear receptor corepressor 2
  • dog(486242) nuclear receptor corepressor 2
  • domestic guinea pig(100720194) nuclear receptor corepressor 2
  • naked mole-rat(101702626) nuclear receptor corepressor 2
  • sheep(101121042) nuclear receptor corepressor 2

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Antibodies

Product Number
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-NCOR2 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry
ChIPAb+ SMRT - przeciwciało i zestaw starterów zweryfikowane pod kątem ChIP, ascites fluid, from mouse,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ChIP
electrophoretic mobility shift assay

immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Przeciwciało anty-SMRTe, Upstate®, from rabbit,
Reaktywność gatunkowa
human
Zastosowanie
ChIP
immunocytochemistry

western blot
Przeciwciało anty-SMRT, klon 1SM-1E7, ascites fluid, clone 1SM-1E7, from mouse,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot

Proteins

Product Number
Opis
Gatunek
NCOR2/SMRT human, recombinant, expressed in E. coli, ≥60% (SDS-PAGE),
Gatunek
human

esiRNA

Product Number
Opis
Gatunek
MISSION® esiRNA, targeting human NCOR2,
Gatunek
human