Skip to Content
Merck
All Photos(1)

Documents

1043003

USP

Ascorbic acid

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

L-Ascorbic acid, L-Threoascorbic acid, Antiscorbutic factor, Vitamin C

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
Molecular Weight:
176.12
Beilstein:
84272
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:

grade

pharmaceutical primary standard

API family

ascorbic acid

manufacturer/tradename

USP

technique(s)

HPLC: suitable

mp

190-194 °C (dec.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Looking for similar products? Visit Product Comparison Guide

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ascorbic acid USP reference standard for specified quality tests and assay use.

Also used to prepare standard, standard stock, system suitability solutions for assay, impurity analysis, and strength according to the given below monographs and general chapters of United States Pharmacopeia (USP):
  • Ascorbic Acid Chewable Gels
  • Ascorbic Acid Compounded Oral Solution
  • Ascorbic Acid Injection
  • Glutathione

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

W Lee et al.
Clinical chemistry, 28(10), 2165-2169 (1982-10-01)
Measurements of ascorbic acid concentration in leukocytes by "high-performance" liquid chromatography (HPLC) provides better nutritional assessment, leading to better management, particularly of presymptomatic and critically ill patients. This procedure includes a simple, reproducible cell-separation technique that requires no more than
Preharvest and postharvest factors influencing vitamin C content of horticultural crops.
Lee, Seung K., and Adel A. Kader.
Postharvest biology and technology, 20.3, 207-220 (2000)
Ascorbic Acid Chewable Gels
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 44(4), 4765-4765 (2019)
Marc P Bradshaw et al.
Critical reviews in food science and nutrition, 51(6), 479-498 (2011-09-21)
Extensive reviews of research are available on the use of ascorbic acid, and its consequent degradation pathways, in physiological conditions or food matrices. However, very little information can be found for wine-related systems. This review highlights the relevant chemistry and
Christopher Grunseich et al.
Neurobiology of disease, 70, 12-20 (2014-06-14)
Spinal and bulbar muscular atrophy (SBMA, Kennedy's disease) is a motor neuron disease caused by polyglutamine repeat expansion in the androgen receptor. Although degeneration occurs in the spinal cord and muscle, the exact mechanism is not clear. Induced pluripotent stem

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service