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52613-U

Supelco

Discovery® DSC-18Lt SPE Tube

bed wt. 500 mg, volume 3 mL, pk of 54

Synonym(s):

Discovery® DSC-18Lt, PK54 3ML 500 mg

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About This Item

UNSPSC Code:
41115712
NACRES:
NB.21

material

polypropylene tube

feature

endcapped

composition

bed wt., 500 mg

packaging

pk of 54

extent of labeling

11% C loading

technique(s)

solid phase extraction (SPE): suitable

surface area

480 m2/g

volume

3 mL

matrix

silica gel base material (irregularly shaped, acid washed)

matrix active group

C18 (octadecyl) bonding

particle size

50 μm

pore size

70 Å pore size

application(s)

food and beverages

separation technique

reversed phase

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General description

Retention Mechanism: Reversed-phase
Sample Matrix Compatibility: Aqueous solutions (biological fluids, water)

  • Monomerically bonded, octadecyl (11 %C), endcapped
  • Increased retention for moderately polar hydrophobic molecules
  • Used to elute very large hydrophobic molecules that are too strongly retained on DSC-18.
  • Offers opportunity to differentiate between drug metabolites in bioanalysis applications
  • Use this less retentive phase for the rapid release of hydrophobic compounds using weaker organic solvents at lower volumes

Legal Information

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Articles

Reversed-phase interaction will retain most molecules with hydrophobic character; it is very useful for extracting analytes that are very diverse in structure within the same sample.

Protocols

HPLC Analysis of Barbiturates in Serum on Discovery® C18 after SPE using Discovery® DSC-18Lt

Chromatograms

application for SPE, application for HPLC

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