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SML1087

Sigma-Aldrich

Sumanirole maleate

≥98% (HPLC)

Synonym(s):

(5R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate, (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate, CID 9818479 maleate, PNU-95,666 maleate

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About This Item

Empirical Formula (Hill Notation):
C11H13N3O · C4H4O4
CAS Number:
179386-44-8
Molecular Weight:
319.31
MDL number:
MFCD09832637
UNSPSC Code:
12352200
PubChem Substance ID:
329825464
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

optical activity

[α]/D -22 to -32°, c = 1 in H2O

storage condition

desiccated

color

white to beige

solubility

H2O: 10 mg/mL, clear

storage temp.

−20°C

SMILES string

O=C1N(C[C@H](NC)C2)C3=C2C=CC=C3N1.O=C(O)/C=C\C(O)=O

InChI

1S/C11H13N3O.C4H4O4/c1-12-8-5-7-3-2-4-9-10(7)14(6-8)11(15)13-9;5-3(6)1-2-4(7)8/h2-4,8,12H,5-6H2,1H3,(H,13,15);1-2H,(H,5,6)(H,7,8)/b;2-1-/t8-;/m1./s1

InChI key

VOJRMYBBPKNLLI-ORHWHDKWSA-N

Application

Sumanirole maleate has been used as a dopamine type 2 receptor (D2R) agonist to study its effects on spatial learning and memory in rats.

Biochem/physiol Actions

Sumanirole is a highly selective and potent dopamine D2 receptor agonist that decreased plasma prolactin levels and depressed dopamine neuron firing rates in the substantia nigra pars compacta. Sumanirole potently stimulates locomotor activity in in animal models of Parkinson′s disease.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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