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Key Documents

SAB5702986

Sigma-Aldrich

Anti-Dystrophin Antibody

rabbit monoclonal, 10G10K7

Synonym(s):

BMD, CMD3B, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
clone:
10G10K7, monoclonal
application:
IF
IHC
species reactivity:
mouse, rat
technique(s):
immunofluorescence: 1:50 - 1:200
immunohistochemistry: 1:50 - 1:200
citations:

Product Name

Anti-Dystrophin Antibody, clone 10G10K7, Rabbit Monoclonal,

biological source

rabbit

Quality Level

material

colorless

clone

10G10K7, monoclonal

form

liquid

species reactivity

mouse, rat

concentration

0.5mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200
immunohistochemistry: 1:50 - 1:200

color

colorless

isotype

IgG

immunogen sequence

LESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... DMD(1756)

General description

This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 3586-3685 of human Dystrophin (P11532).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

IHC, IF/ICC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1


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