SAB3500306

Anti-Slc22A17 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-BOCT, Anti-BOIT, Anti-Brain-type organic cation transporter, Anti-Solute carrier family 22 member 17
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: predicted mol wt 59 kDa
• species reactivity: rat, human, mouse
• technique(s): immunohistochemistry: suitable; indirect ELISA: suitable; indirect immunofluorescence: suitable; western blot: suitable
• NCBI accession no.: Q8WUG5
• UniProt accession no.: Q8WUG5
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... SLC22A17(51310)

Description

General description

Slc22A17 gene is also referred to as brain organic cation transporter (BOCT) and is mapped to human chromosome 14q11.2. The encoded protein is predominantly localized to kidney and liver. The Slc22 proteins consists of 12 transmembrane (TM) α-helices with an extended loop (extracellular) between the first and the second transmembrane regions, and a loop (intracellular) between the sixth and the seventh transmembrane regions.

Immunogen

Slc22A17 antibody was raised against a 14 amino acid peptide near the carboxy terminus of the human Slc22A17.

Biochem/physiol Actions

Slc22A17 expression is associated with important biological processes such as cell differentiation, apoptosis and inflammation. Slc22A17 mediates endocytosis of neutrophil gelatinase-associated lipocalin, a mammalian protein that can bind to bacterial siderophore enterobactin with high affinity.

Features and Benefits

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Linkage

The action of this antibody can be blocked using blocking peptide SBP3500306.

Physical form

Supplied in PBS with 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable