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Key Documents

LSMLS

Sigma-Aldrich

Large Scale Metabolite Library

Supplied by IROA Technologies

Synonym(s):

Mass Spectrometry Metabolite Library, LSMLS, Large Scale Metabolite Library of Standards, Metabolic Library, Metabolite Library, primary metabolites

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About This Item

UNSPSC Code:
41116107

packaging

pkg of 7 plates

manufacturer/tradename

IROA Technologies

plate size

96 wells

shipped in

dry ice

storage temp.

−20°C

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General description

LSMLS (Large Scale Metabolite Library of Standards) is a collection of high quality small biochemical molecules that span a broad range of primary metabolism. These are high purity (>95%) compounds supplied in an economical, ready-to-use format. This library of standards is most commonly used for metabolite qualification and quantification for MS and NMR, functional cellular assays and phenotypic screening. Metabolite descriptors provided with product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Substance ID.

The library is intended to be used for mass spectrometry metabolomics applications and provides a broad representation of primary metabolism.

Application

Metabolite qualification and quantification for MS, NMR, etc.
Functional cellular assays
Phenotypic screening

Features and Benefits

Over 500 unique small molecule metabolites organized in a 96-well format.

To view a complete list of compounds in the library for recent lots, download the plate maps below:
The complete plate map with name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMBD ID, PubChem Compound and Substance ID are provided with the software dowmload.

Broad metabolite spectrum, key primary metabolites and intermediates covering key metabolic pathways, including the following classes of compounds:
  • Carboxylic acids, amino acids
  • Biogenic amines, polyamines
  • Nucleotides, coenzymes and vitamins
  • Mono-and disaccharides; Fatty acids, lipids, steroids and hormones

Suitability

Suitable for manual and automated work flows.

Preparation Note

LSMLS compounds are conveniently provided at 1mg per well, enough for multiple injections. Compounds can either be used as standards and injected individually or a strategy may be employed to pool compounds by row to allow multiple mixtures to be analyzed per injection. For more information on LSMLS, solubilization and preparation notes please refer to the product information sheet at the top of the page.

Other Notes

MLSDiscovery software package is distributed with and is tailored to work with LSMLS. A user manual and video instructions are provided.
To download the software package, click here - MLSDiscovery software.

To view the MLSDiscovery Video visit: MLSDiscovery Tutorial Video.

Legal Information

LSMLS is a trademark of IROA Technologies LLC
MLSDiscovery is a trademark of IROA Technologies LLC

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Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Eye Dam. 1 - Lact. - Muta. 2 - Repr. 1A - Resp. Sens. 1 - Skin Corr. 1 - Skin Sens. 1 - STOT RE 1 - STOT RE 2 Oral - STOT SE 2 - STOT SE 3

Target Organs

Blood, Immune system, Respiratory system

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Charles M Nichols et al.
Analytical chemistry, 90(24), 14484-14492 (2018-11-20)
In this work, we established a collision cross section (CCS) library of primary metabolites based on analytical standards in the Mass Spectrometry Metabolite Library of Standards (MSMLS) using a commercially available ion mobility-mass spectrometer (IM-MS). From the 554 unique compounds

Related Content

We provide small molecule metabolite libraries and kits with a comprehensive range of primary metabolite compounds covering key metabolic pathways for your metabolomics research.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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