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Key Documents

L7414

Sigma-Aldrich

N-Lauroylsarcosine sodium salt solution

20%, for molecular biology

Synonym(s):

Sarcosyl, Sarkosyl NL, Sodium N-dodecanoyl-N-methylglycinate, Sodium N-lauroylsarcosinate solution

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About This Item

Linear Formula:
CH3(CH2)10CON(CH3)CH2COONa
CAS Number:
Molecular Weight:
293.38
Beilstein:
5322974
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.25

grade

for molecular biology

Quality Level

description

anionic

mol wt

293.38 g/mol

concentration

19-21% (Titration by HClO4)
20%

foreign activity

DNase, RNase, and protease, none detected

SMILES string

[Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O

InChI

1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1

InChI key

KSAVQLQVUXSOCR-UHFFFAOYSA-M

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General description

N-Lauroylsarcosine sodium salt solution is an anionic surfactant which can be used in DNA extraction.

Application

N-Lauroylsarcosine sodium salt has been used in a study to assess the mechanisms underlying surfactant-induced itching. It has also been used in a study to investigate the formation of pH-responsive, stable vesicles resulting from an interaction with N-cetylpyridinium chloride (CPC) and N-dodecylpyridinium chloride (DPC) in aqueous mixtures.

Features and Benefits

N-Lauroylsarcosine does not precipitate and is commonly used in place of SDS.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

512.6 °F

Flash Point(C)

267 °C


Certificates of Analysis (COA)

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Interaction of sodium N-lauroylsarcosinate with N-alkylpyridinium chloride surfactants: Spontaneous formation of pH-responsive, stable vesicles in aqueous mixtures
Ghosh, S. and J. Dey
Journal of Colloid and Interface Science, 358, 9-9 (2011)
Emanuele Gabellieri et al.
European journal of medicinal chemistry, 204, 112615-112615 (2020-08-11)
The compound screening was initiated with a direct staining assay to identify compounds binding to Tau aggregates and not Abeta plaques using human brain sections derived from late stage Alzheimer's disease donors. The binding of Tau aggregate selective compounds was
Luoquan Li et al.
ACS sensors, 4(5), 1299-1305 (2019-05-03)
Droplet microfluidics-based platform (Drop-seq) has been shown to be a powerful tool for single cell expression profiling. Nevertheless, this platform required the simultaneous encapsulation of single cell and single barcoded bead, the incidence of which was very low, limiting its
Takahiro Sekikawa et al.
New biotechnology, 29(1), 139-143 (2011-09-20)
Detection of low amounts of Cryptosporidium oocysts in raw water sources is considered an important component in the management, prevention and control of Cryptosporidium in drinking water supplies as Cryptosporidium causes massive waterborne outbreaks worldwide. As Cryptosporidium has a robust
Yoshihiro Inami et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 132(11), 1225-1230 (2012-11-06)
The primary function of surfactants is to remove dirt, exfoliated corneum cells, and microorganisms from the skin. However, the use of toiletries such as soaps and shampoos containing surfactants may cause adverse effects such as cutaneous irritation, dryness, and itching.

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