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Key Documents

C0856

Sigma-Aldrich

C7BzO

Synonym(s):

3-(4-Heptyl)phenyl-3-hydroxypropyl)dimethylammoniopropanesulfonate

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About This Item

Empirical Formula (Hill Notation):
C21H37NO4S
Molecular Weight:
399.59
MDL number:
UNSPSC Code:
12161902
PubChem Substance ID:
NACRES:
NA.56

description

zwitterionic

Quality Level

Assay

≥95.0% (HPLC)

form

solid

mol wt

399.59 Da (anhydrous)

aggregation number

≤25

technique(s)

dialysis: suitable
electrophoresis: suitable
protein quantification: suitable

SMILES string

CCCCCCCc1ccc(cc1)C(O)CC[N+](C)(C)CCCS([O-])(=O)=O

InChI

1S/C21H37NO4S/c1-4-5-6-7-8-10-19-11-13-20(14-12-19)21(23)15-17-22(2,3)16-9-18-27(24,25)26/h11-14,21,23H,4-10,15-18H2,1-3H3

InChI key

FUPYROAFYPQUSH-UHFFFAOYSA-N

General description

3-(4-heptyl)phenyl 3-hydroxypropyl dimethyl ammonio propane sulfonate (C7BzO) is a zwitterionic detergent comprising of a zwitterionic, hydrophilic head connected to the hydrophobic tail through a linker region. The prelinker region enhances detergent solubility. C7BzO is effective in sample preparation from plant membranes.

Application

C7BzO has been used as a component of extraction solution for protein isolation from mycelia and recombinant mammalian prion proteins.

Other Notes

Zwitterionic detergent; especially well-suited to protein extraction for proteomics applications.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yang Yang et al.
Journal of biochemistry and molecular biology, 39(2), 145-149 (2006-04-06)
To analyze the effect of Maltol on the apoptosis of Human Neuroblastoma Cells (SH-SY5Y) treated by free radical which was generated from Hydrogen Peroxide (H2O2), flow cytometry analysis on Phosphatidylserine (PS) inverting percentage was applied to determine the apoptosis. MTT
Evaluation of nonionic and zwitterionic detergents as membrane protein solubilizers in two-dimensional electrophoresis
Luche S, et al.
Proteomics, 3(3), 249-253 (2003)
Anders S Andersen et al.
The Journal of antimicrobial chemotherapy, 65(8), 1646-1654 (2010-06-15)
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Acta biochimica Polonica, 66(3), 343-350 (2019-09-12)
Two winter triticale (x Triticosecale Wittmack) model cultivars: Hewo (tolerant to pink snow mould) and Magnat (sensitive) were used to test the effect of cold-hardening (4 weeks at 4°C) on soluble ≤50 kDa protein profiles of the seedling leaves. The
Cristina-Maria Vâlcu et al.
Proteomics, 6(14), 4166-4175 (2006-06-23)
Protein extraction from plant samples is usually challenging due to the low protein content and high level of contaminants. Therefore, the 2-DE pattern resolution is strongly influenced by the procedure of sample preparation. Efficient solubilization of proteins strictly depends on

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