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Key Documents

19459

Sigma-Aldrich

Protein G recombinant

from Escherichia coli, ≥90%

Synonym(s):

IgG F(c)-Receptor

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.77

biological source

Escherichia coli

Quality Level

mol wt

Mr ~31800

concentration

≥90%

storage temp.

−20°C

General description

Protein G is a small globular cell surface protein produced by Streptococcus sp. It is composed of two or three nearly identical domains of 55 amino acids each. It binds to Fc fragment of IgG from many species with high affinity. It does not recognize IgM, IgA, IgE or serum albumin.

Physical form

lyophilized powder in PBS, pH 7.4

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Robert Carlisle et al.
Pharmaceutical research, 30(2), 352-361 (2012-09-21)
To improve the delivery of liposomes to tumors using P-selectin glycoprotein ligand 1 (PSGL1) mediated binding to selectin molecules, which are upregulated on tumorassociated endothelium. PSGL1 was orientated and presented on the surface of liposomes to achieve optimal selectin binding

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