Skip to Content
Merck
All Photos(3)

Documents

S1804

Sigma-Aldrich

Trisodium citrate dihydrate

meets USP testing specifications

Synonym(s):

Sodium citrate tribasic dihydrate, Citric acid trisodium salt dihydrate, Trisodium citrate dihydrate

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
HOC(COONa)(CH2COONa)2 · 2H2O
CAS Number:
Molecular Weight:
294.10
Beilstein:
6104939
EC Number:
MDL number:
UNSPSC Code:
12352300
PubChem Substance ID:
NACRES:
NA.21

Agency

meets USP testing specifications

Quality Level

Assay

99.0-100.5% anhydrous basis

form

powder

pH

7.5-9 (25 °C, 29.4 g/L)

mp

>300 °C (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

InChI

1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3

InChI key

NLJMYIDDQXHKNR-UHFFFAOYSA-K

Looking for similar products? Visit Product Comparison Guide

Application


  • Coumarin derivative-functionalized nanoporous silica as an on-off fluorescent sensor for detecting Fe(3+) and Hg(2+) ions: a circuit logic gate.: This study explores the utilization of Trisodium citrate dihydrate in the synthesis of nanoporous silica for the development of a fluorescent sensor. This sensor demonstrates potential applications in environmental monitoring and biomedical diagnostics, particularly for detecting hazardous metal ions (Mousavi et al., 2024).

  • Silver Nanoparticles-Chitosan Nanocomposites: A Comparative Study Regarding Different Chemical Syntheses Procedures and Their Antibacterial Effect.: Research discusses the role of Trisodium citrate dihydrate in the synthesis of silver nanoparticles embedded in chitosan, emphasizing its efficacy in creating potent antibacterial agents suitable for various medical and industrial applications (Chicea et al., 2024).

  • Improved production of andrimid in Erwinia persicina BST187 strain by fermentation optimization.: Demonstrates the application of Trisodium citrate dihydrate in optimizing fermentation processes to enhance the production of andrimid, a bioactive compound with significant pharmaceutical potential (Cheng et al., 2023).

  • Fabrication of Ag nanostar and PEI-based SERS substrate for sensitive and rapid detection of SO(2): Application for detection of sulfite residues in beer.: Highlights the innovative use of Trisodium citrate dihydrate in the fabrication of specialized substrates for the rapid and sensitive detection of sulfite residues in beverages, underlining its importance in food safety and quality assurance (Kitaw et al., 2023).


Biochem/physiol Actions

Citrate is a intermediate in the TCA cycle and fatty acid synthesis. Citrate is an allosteric modulator of acetyl-CoA carboxylase, the enzyme that regulates the conversion of acetyl-CoA to malonyl-CoA.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Simona Pedrotti et al.
Science advances, 5(4), eaav1472-eaav1472 (2019-04-20)
Obesity and its associated metabolic abnormalities have become a global emergency with considerable morbidity and mortality. Epidemiologic and animal model data suggest an epigenetic contribution to obesity. Nevertheless, the cellular and molecular mechanisms through which epigenetics contributes to the development
Marin Ming et al.
Vaccine, 37(22), 2960-2966 (2019-04-24)
Potency assays for vaccine products are an important regulatory requirement, and are used to assess product quality and consistency prior to lot release for clinical testing. Ideally they measure an established correlate of efficacy or protection. In cases where there
Céleste-Élise Stephany et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(35), 11631-11640 (2014-08-29)
The closure of developmental critical periods consolidates neural circuitry but also limits recovery from early abnormal sensory experience. Degrading vision by one eye throughout a critical period both perturbs ocular dominance (OD) in primary visual cortex and impairs visual acuity
Jun Zhao et al.
Nanotechnology, 25(40), 405101-405101 (2014-09-12)
The treatment of liver injuries or hepatocellular carcinoma (HCC) has been hindered by the lack of efficient drug delivery. Even with the help of nanoparticles or other synthetic delivering agents, a large portion of the dose is still sequestered in
Stijn Mertens et al.
Applied and environmental microbiology, 81(23), 8202-8214 (2015-09-27)
Lager beer is the most consumed alcoholic beverage in the world. Its production process is marked by a fermentation conducted at low (8 to 15°C) temperatures and by the use of Saccharomyces pastorianus, an interspecific hybrid between Saccharomyces cerevisiae and

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service