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Key Documents

N2515

Supelco

D-Norpropoxyphene maleate salt

analytical standard

Synonym(s):

1,2-Diphenyl-3-methyl-4-(methylamino)-2-butyl propionate

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About This Item

Empirical Formula (Hill Notation):
C21H27NO2 · C4H4O4
CAS Number:
Molecular Weight:
441.52
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

OC(=O)\C=C/C(O)=O.CCC(=O)OC(Cc1ccccc1)(C(C)CNC)c2ccccc2

InChI

1S/C21H27NO2.C4H4O4/c1-4-20(23)24-21(17(2)16-22-3,19-13-9-6-10-14-19)15-18-11-7-5-8-12-18;5-3(6)1-2-4(7)8/h5-14,17,22H,4,15-16H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

HCQPFYNZJNOOKN-BTJKTKAUSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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J W King et al.
Journal of analytical toxicology, 18(4), 217-219 (1994-07-01)
We have found that in using the Toxi-Lab Spec VC MP3 column we were able to easily identify and quantitate both propoxyphene and the major metabolite, norpropoxyphene, in a single extraction using urine as a matrix. Samples were screened using
F T Horrigan et al.
The Journal of general physiology, 107(2), 243-260 (1996-02-01)
Voltage-dependent ionic currents were recorded from squid giant fiber lobe neurons using the whole-cell patch-clamp technique. When applied to the bathing solution, methadone was found to block IK, I Na and I Ca. Both I Na and I Ca were
R J Flanagan et al.
British journal of clinical pharmacology, 28(4), 463-469 (1989-10-01)
1. The pharmacokinetics of dextropropoxyphene (D) and nordextropropoxyphene (ND) have been studied in 12 healthy young (21-28 years) and 12 healthy elderly (70-79 years) male and female subjects. Each received 65 mg D and plasma D and ND concentrations were
Y Horsmans et al.
Journal of hepatology, 21(3), 283-291 (1994-09-01)
In an attempt to design a liver function test which takes into account both portal-systemic shunting and hepatocellular dysfunction, we investigated a group of patients with cirrhosis with or without surgical porta-caval shunt for d-propoxyphene and its major metabolite, norpropoxyphene
P P Rop et al.
Journal of chromatography, 615(2), 357-364 (1993-06-02)
Dextromoramide, propoxyphene and its main metabolite, norpropoxyphene, were determined in blood after solid-liquid extraction by means of an HPLC method using photodiode-array detection. Two cases of fatal overdose resulting from abuse of the two drugs are presented. In case 1

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