B34656

Biphenyl

ReagentPlus^®, 99.5%

• Synonym(s): 1,1′-Biphenyl, Diphenyl
• Linear Formula: C₆H₅C₆H₅
• CAS Number: 92-52-4
• Molecular Weight: 154.21
• Beilstein: 1634058
• EC Number: 202-163-5
• MDL number: MFCD00003054
• UNSPSC Code: 12352100
• PubChem Substance ID: 24891720
• NACRES: NA.21

Properties

• vapor density: 5.31 (vs air)
• Quality Level: 100
• vapor pressure: 9.46 mmHg ( 115 °C)
• product line: ReagentPlus^®
• Assay: 99.5%
• form: flakes; powder or crystals
• autoignition temp.: 1004 °F
• expl. lim.: 0.6 %, 111 °F; 5.8 %, 166 °F
• bp: 255 °C (lit.)
• mp: 68-70 °C (lit.)
• SMILES string: c1ccc(cc1)-c2ccccc2
• InChI: 1S/C12H10/c1-3-7-11(8-4-1)12-9-5-2-6-10-12/h1-10H
• InChI key: ZUOUZKKEUPVFJK-UHFFFAOYSA-N
• Gene Information: human ... CYP1A2(1544) , ESR1(2099)

Description

General description

Biphenyl (BP) is a p-polyphenyl containing two phenyl rings with a non-planar conformation. Its synthesis from benzene by intermolecular direct C-H homocoupling in the presence of palladium-containing catalytic system has been described. Stereochemical studies of its structure have been reported. The nitration of BP using 95% nitric acid to form mononitrobiphenyl isomers has been investigated.

Application

• Application of Sublimation in the Synthesis and Crystal Growth of Organosulfones: Utilizing sublimation techniques for the synthesis and growth of organosulfone crystals, this study demonstrates how biphenyl derivatives can be integrated into advanced material science applications (Refat et al., 2024).
• Bicarbazole-Benzophenone Based Twisted Donor-Acceptor Derivatives: Research on bicarbazole-benzophenone derivatives highlights their role as potential blue thermally activated delayed fluorescence emitters for OLED applications, showcasing the utility of biphenyl frameworks in the development of electronic materials (Siddiqui et al., 2024).
• Optimization of Gas Chromatography Methods for Organic Contaminants: A study details the optimization of a gas chromatography method coupled with Orbitrap mass spectrometry, emphasizing the detection of biphenyl-based organic contaminants in biological samples, crucial for environmental monitoring (Oró-Nolla et al., 2024).
• Enhanced Solubility and Bioavailability of Antifungal Agents: This investigation presents how biphenyl structures can improve the solubility and bioavailability of clotrimazole, proposing enhanced antifungal treatments through the use of hydrophobized hyperbranched polyglycidol (Jaworska-Krych et al., 2024).
• Bioremediation of Persistent Organic Pollutants: A systematic review discusses the use of microalgae-bacteria consortia for the bioremediation of biphenyl-containing persistent organic pollutants, providing a sustainable approach to environmental cleanup (Guo et al., 2024).

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H315 - H319 - H335 - H410
• Precautionary Statements: P261 - P264 - P271 - P273 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 2
• Flash Point(F): 230.0 °F - closed cup
• Flash Point(C): 110 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves