80821

(2S)-2-(5-Iodo-6-methoxynaphthalen-2-yl)propanoic acid

pharmaceutical impurity standard

• Synonym(s): Naproxen Impurity D (PhEur), (αS)-5-Iodo-6-methoxy-α-methyl-2-naphthaleneacetic acid, (2S)-2-(5-Iodo-6-methoxy-2-naphthyl)propionic acid, (S)-5-Iodo naproxen, Naproxen EP Impurity D
• Empirical Formula (Hill Notation): C₁₄H₁₃IO₃
• CAS Number: 116883-62-6
• Molecular Weight: 356.16
• MDL number: MFCD27967014
• UNSPSC Code: 12352200
• PubChem Substance ID: 329769058
• NACRES: NA.24

Properties

• Quality Level: 100
• API family: naproxen
• Assay: ≥98.0% (HPLC)
• optical activity: [α]/D 41±4°, c = 1 in chloroform
• shelf life: limited shelf life, expiry date on the label
• impurities: ≤0.5% water
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: C[C@H](C(O)=O)C1=CC2=CC=C(OC)C(I)=C2C=C1
• InChI: 1S/C14H13IO3/c1-8(14(16)17)9-3-5-11-10(7-9)4-6-12(18-2)13(11)15/h3-8H,1-2H3,(H,16,17)/t8-/m0/s1
• InChI key: MNTGUQDQTXNYMT-QMMMGPOBSA-N

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301
• Precautionary Statements: P301 + P330 + P331 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable