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11074440001

Roche

Penicillin-Streptomycin

suitable for cell culture, lyophilized (clear, colorless solution after reconstitution), non-sterile; 0.2 μm filtered, sufficient for 20 mL

Synonym(s):

antibiotic

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About This Item

UNSPSC Code:
12352207

sterility

non-sterile; 0.2 μm filtered

Quality Level

100

form

lyophilized (clear, colorless solution after reconstitution)

usage

sufficient for 20 mL

manufacturer/tradename

Roche

concentration

50 mg/mL streptomycin in 0.9% NaCl (as sulfate)
50,000 U/mL penicillin in 0.9% NaCl

technique(s)

cell culture | mammalian: suitable

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

Mode of action

cell wall synthesis | interferes
protein synthesis | interferes

storage temp.

2-8°C

Related Categories

General description

Cytotoxic concentration: 10,000 IU/ml penicillin, 20 mg/ml streptomycin
Penicillin (Penicillin G) inhibits bacterial growth by inhibiting peptidoglycan synthesis. Streptomycin belongs to the family of aminoglycoside antibiotics, and inhibits bacterial growth by inhibiting protein synthesis. Penicillin-Streptomycin is used for the prevention and elimination of bacterial contaminants in cell culture.
Penicillin G, sodium salt; streptomycin sulfate
Sensitive organisms:
  • Gram-positive bacteria (penicillin)
  • Gram-negative bacteria (streptomycin)
  • Stability:Penicillin: 3 days
  • Streptomycin: 3 days in media at +37 °C

Application

Penicillin-Streptomycin has been used for the prevention and elimination of bacterial contaminants in cell culture.

Physical form

Lyophilizate, 50,000 U/ml penicillin G and 50 mg/ml streptomycin (as sulfate) in 0.9% NaCl

Preparation Note

Working concentration: 100 IU/ml penicillin
100 μg/ml streptomycin

Reconstitution

Dissolve in 20mL distilled water.

Other Notes

For life science research only. Not for use in diagnostic procedures.

Pictograms

Exclamation markHealth hazard
GHS07,GHS08

Signal Word

Danger

Hazard Statements

H302,H317,H334,H361d

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2 - Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

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Certificates of Analysis (COA)

Lot/Batch Number
72248400
59347800
39189500
46944600
13377820

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Lysozyme and penicillin inhibit the growth of anaerobic ammonium-oxidizing planctomycetes.
Hu Z, et al.
Applied and Environmental Microbiology, 79(24), 7763-7769 (2013)
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American journal of physiology. Gastrointestinal and liver physiology, 318(4), G705-G716 (2020-02-25)
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Global Trade Item Number

SKUGTIN
110744400014061838698261

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