AB1526P
Anti-Nerve Growth Factor-β Antibody, pain
Chemicon®, from rabbit
Synonym(s):
NGFbeta
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
chicken, human, mouse, rat
should not react with
bovine
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... NGF(4803)
Specificity
Nerve growth factor-beta (NGF). Less than 1% cross-reactivity against recombinant human BDNF, NT3 and NT4 by ELISA.
Immunogen
Mouse nerve growth factor-beta purified from salivary glands.
Application
Immunohistochemistry: 1-2 μg/mL (see suggested protocol).
Immunoblotting: 1-2 μg/mL
Bioassays (Inhibition of biological activity in vitro): 1-2 μg/mL
in vivo animal studies: use neat
ELISA: 1-2 μg/mL
Optimal working dilutions must be determined by the end user.
BIOLOGICAL ACTIVITY:
This antibody completely inhibits neuron survival and the outgrowth actions of mouse NGF in chicken dorsal root ganglion in vitro.
Immunoblotting: 1-2 μg/mL
Bioassays (Inhibition of biological activity in vitro): 1-2 μg/mL
in vivo animal studies: use neat
ELISA: 1-2 μg/mL
Optimal working dilutions must be determined by the end user.
BIOLOGICAL ACTIVITY:
This antibody completely inhibits neuron survival and the outgrowth actions of mouse NGF in chicken dorsal root ganglion in vitro.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
Neurochemistry & Neurotrophins
This Anti-Nerve Growth Factor-β Antibody, pain is validated for use in ELISA, WB, IH, FUNC for the detection of Nerve Growth Factor-β.
Linkage
Replaces: 04-1119
Physical form
Affinity purified immunoglobulin. Lyophilized from PBS. Contains no preservative. Reconstitute to desired volume with sterile distilled water. Suggested concentration 0.5-1.0 mg/mL.
Storage and Stability
Maintain at lyophilized material at -20 to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20 to -70°C in undiluted aliquots for up to six months. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Chronic nicotine administration increases NGF-like immunoreactivity in frontoparietal cerebral cortex.
R Martinez-Rodriguez, A Toledano, M I Alvarez, L Turegano, O Colman, P Roses et al.
Journal of Neuroscience Research null
Nerve growth factor of cultured medium extracted from human degenerative nucleus pulposus promotes sensory nerve growth and induces substance p in vitro.
Kazuyo Yamauchi,Gen Inoue,Takana Koshi,Masaomi Yamashita,Toshinori Ito,Munetaka Suzuki et al.
Spine null
T Nishio et al.
Neuroscience, 60(1), 67-84 (1994-05-01)
To elucidate the role and the mechanism of action of nerve growth factor in the adult central nervous system, we investigated the localization of nerve growth factor-like immunoreactivity in adult rat brain, both quantitatively and immunohistochemically, using polyclonal anti-nerve growth
Immunohistochemical distribution of NGF, BDNF, NT-3, and NT-4 in adult rhesus monkey brains.
Zhang, HT; Li, LY; Zou, XL; Song, XB; Hu, YL; Feng, ZT; Wang, TT
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society null
Biochemical effects of antibodies against nerve growth factor on developing and differentiated sympathetic ganglia.
M Goedert et al.
Brain research, 148(1), 264-268 (1978-06-09)
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