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612075

Sigma-Aldrich

Thyroxine-Binding Globulin, Human

Liver glycoprotein and a major thyroid hormone carrier in serum. Exhibits high sequence similarity with α1-antitrypsin.

Synonym(s):

hTBG

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About This Item

UNSPSC Code:
12352202

Quality Level

Assay

≥95.0% (SDS-PAGE)

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

shipped in

wet ice

storage temp.

−20°C

General description

M.W. 54,000-64,000.
Native, human thyroxine-binding globulin. Liver glycoprotein and a major thyroid hormone carrier in serum. Exhibits high sequence similarity with α1-antitrypsin. Its affinity for the hormone is thought to be temperature-sensitive.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In 140 mM NaCl, 10 mM Tris, 0.1% NaN₃, pH 8.0. Sterile-filtered.

Preparation Note

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Miura, Y., et al. 1993. Endocrinol. J. 40, 127.
Janssen, O.E., et al. 1992. J. Biol. Chem.267, 13998.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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