475893

MES

ULTROL^® Grade, ≥99% dry basis (titration), zwitterionic buffer useful in pH range 5.5-6.5

• Synonym(s): MES, Free Acid, ULTROL^® Grade, 2-(N-Morpholino)ethanesulfonic Acid
• Empirical Formula (Hill Notation): C₆H₁₃NO₄S
• CAS Number: 4432-31-9
• Molecular Weight: 195.24
• MDL number: MFCD00006181
• UNSPSC Code: 12161704

Properties

• Quality Level: 200
• Assay: ≥99% dry basis (titration)
• form: crystalline solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic)
• color: white
• pKa (20 °C): 6.2
• solubility: water: 1.0 M (195.2 mg/ml)
• cation traces: heavy metals: ≤1 ppm
• shipped in: ambient
• storage temp.: 15-25°C
• InChI: 1S/C6H13NO4S/c8-12(9,10)6-3-7-1-4-11-5-2-7/h1-6H2,(H,8,9,10)
• InChI key: SXGZJKUKBWWHRA-UHFFFAOYSA-N

Description

General description

A zwitterionic buffer useful in the pH range of 5.5-6.5 (absorbance: <0.05 at 260 nm, 1.0 M, H₂O; pKa: 6.1 ± 0.2 at 25°C).

A zwitterionic buffer useful in the pH range of 5.5-6.5. Has a pK_a of 6.10 at 25°C.

Absorbance (1.0 M, H₂O, 260 nm): <0.05.

Application

• Preformulation Characterization, Stabilization, and Formulation Design for the Acrylodan-Labeled Glucose-Binding Protein SM4-AC.: This study focuses on the preformulation characterization, stabilization, and formulation of the acrylodan-labeled glucose-binding protein SM4-AC, highlighting the use of MES buffer in the process (Sahni et al., 2017).


• Evidences for Chlorogenic Acid--A Major Endogenous Polyphenol Involved in Regulation of Ripening and Senescence of Apple Fruit.: The research investigates the role of chlorogenic acid in the ripening and senescence of apple fruit, utilizing MES buffer in various biochemical assays (Xi et al., 2016).


• The interaction of nifedipine with selected cyclodextrins and the subsequent solubility-permeability trade-off.: This article examines the interactions between nifedipine and cyclodextrins, emphasizing the solubility-permeability trade-off and using MES buffer in experimental setups (Beig et al., 2013).


• Capillary electrophoresis microchips for separation and detection of organophosphate nerve agents.: This research uses MES buffer in capillary electrophoresis microchips for the separation and detection of organophosphate nerve agents (Wang et al., 2001).

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 2 weeks at 4°C.

Other Notes

Good, N.E., et al. 1966. Biochemistry 5, 467.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable