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07-002

Sigma-Aldrich

Anti-p67-phox Antibody

serum, Upstate®

Synonym(s):

Anti-NCF-2, Anti-NOXA2, Anti-P67-PHOX, Anti-P67PHOX

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_000433

UniProt accession no.

P19878

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... NCF2(4688)

Specificity

p67-phox

Immunogen

GST fusion protein corresponding to full-length human p67-phox.

Application

Research Category
Neuroscience
Research Sub Category
Oxidative Stress
This Anti-p67-phox Antibody is validated for use in IP, WB, IC for the detection of p67-phox.

Quality

routinely evaluated by immunoblot on RIPA lysates from HL-60 cells

Target description

65kDa

Physical form

Antiserum
rabbit antiserum containing 0.05% azide

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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INF-? Enhances Nox2 Activity by Upregulating phox Proteins When Applied to Differentiating PLB-985 Cells but Does Not Induce Nox2 Activity by Itself.
Ellison, MA; Thurman, G; Gearheart, CM; Seewald, RH; Porter, CC; Ambruso, DR
Testing null
Katherine A Gauss et al.
Journal of leukocyte biology, 71(2), 319-328 (2002-01-31)
The NADPH oxidase plays an important role in immune and nonimmune cell functions. Because rabbits represent an established model for studying a number of important disease processes that involve NADPH oxidase activity, we carried out studies to clone and sequence
Aswathy M Cheriyan et al.
American journal of physiology. Renal physiology, 320(5), F789-F798 (2021-02-23)
Calcineurin inhibitors (CNIs) are vital immunosuppressive therapies in the management of inflammatory conditions. A long-term consequence is nephrotoxicity. In the kidneys, the primary, catalytic calcineurin (CnA) isoforms are CnAα and CnAβ. Although the renal phenotype of CnAα-/- mice substantially mirrors
Brian M Barth et al.
Journal of neuroscience research, 90(1), 229-242 (2011-09-21)
Inflammation accompanied by severe oxidative stress plays a vital role in the orchestration and progression of neurodegeneration prevalent in chronic and acute central nervous system pathologies as well as in aging. The proinflammatory cytokine tumor necrosis factor-α (TNFα) elicits the
Localization of a constitutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: enhancement by angiotensin II
Pagano, P J, et al
Proceedings of the National Academy of Sciences of the USA, 94, 14483-14488 (1997)
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