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850850P

Avanti

18:1 Monomethyl PE

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-methyl, powder

Synonym(s):

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine-N-methyl

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About This Item

Empirical Formula (Hill Notation):
C42H80NO8P
CAS Number:
Molecular Weight:
758.06
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (850850P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850850P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[N+](C)([H])[H])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O

InChI

1S/C42H80NO8P/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-41(44)48-38-40(39-50-52(46,47)49-37-36-43-3)51-42(45)35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-5-2/h18-21,40,43H,4-17,22-39H2,1-3H3,(H,46,47)/b20-18+,21-19+/t40-/m1/s1

InChI key

LPXFOQGBESUDAX-KFVQOHGZSA-N

General description

18:1 Monomethyl phosphoethanolamine (PE) is an alkyl phosphate derivative. Methyl transferases catalyzes the formation of monomethyl PE by acting on PE. It might be involved in the transduction of biochemical signals via the cell membrane.

Application

18:1 Monomethyl PE may be used for the preparation of standard liposomes. It is also suitable to study its effect on the interaction of fructan with monomolecular lipid system.

Packaging

5 mL Clear Glass Sealed Ampule (850850P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Membrane Fluidity (2012)
Grzegorz Pawlik et al.
The Journal of biological chemistry, 295(8), 2473-2482 (2020-01-15)
Phospholipid N-methyltransferases (PLMTs) synthesize phosphatidylcholine by methylating phosphatidylethanolamine using S-adenosylmethionine as a methyl donor. Eukaryotic PLMTs are integral membrane enzymes located in the endoplasmic reticulum (ER). Recently Opi3, a PLMT of the yeast Saccharomyces cerevisiae was proposed to perform in
Structural requirements of the fructan-lipid interaction
Vereyken IJ, et al.
Biophysical Journal, 84(5), 3147-3154 (2003)
Effects of lipids on the interaction of SecA with model membranes
Ahn T, et al.
Archives of Biochemistry and Biophysics, 395(1), 14-20 (2001)

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