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JKA0003

Sigma-Aldrich

Y-PEG40K-Acetaldehyde

average Mn 40,000

Synonym(s):

Y-PEG-Acetaldehyde

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About This Item

Linear Formula:
(CH3O(CH2CH2O)nCH2CH2)(CH3O(CH2CH2O)nCH2CO)NCH2CONHCH2COH
UNSPSC Code:
12162002
NACRES:
NA.23

form

solid

mol wt

average Mn 40,000

reaction suitability

reactivity: N-terminal amine reactive
reactivity: amine reactive

polymer architecture

shape: Y-shape
functionality: monofunctional

storage temp.

−20°C

General description

Y-shaped Acetaldehyde PEG. N-terminal amine reactive PEG in the presence of a reducing reagent; less reactive but more selective compared to linear PEG aldehydes; reacts at pH 5-8. JenKem Technology′s patented products, Y-shape PEG derivatives, also known as branched PEG derivatives, contain two linear methoxy PEG chains attached to a central active core. JenKem proprietary Y-shape PEGs are more selective, due to their sterically bulky structure.

Application

Applications may include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization

Legal Information

Product of JenKem Technology

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Articles

Applications of Y-Shape Peg Derivatives for Drug Delivery

The immune system protects the body from disease by resisting the invasion of foreign molecules into its cells, for example peptides and proteins are hydrolyzed by proteolytic enzymes; nucleic acids are hydrolyzed by nucleases; and most small molecules are eliminated in the liver and kidneys.

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