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932574

Sigma-Aldrich

Poly(oligo(ethylene glycol) methyl ether methacrylate) 300

average Mw 40 kDa

Synonym(s):

POEGMA, Poly(oligo(ethylene glycol) methacrylate)

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About This Item

Linear Formula:
C6H8NO2[C4H5O2(C2H4O)x]nOH
UNSPSC Code:
12162002
NACRES:
NA.23

product name

Poly(oligo(ethylene glycol) methyl ether methacrylate) 300, average Mw 40 kDa

form

viscous liquid

Quality Level

100

mol wt

average Mw 40 kDa

color

clear colorless to pale yellow

storage temp.

−20°C

General description

Poly(oligo(ethylene glycol) methacrylate) (POEGMA) 300 is a family of polymers consisting of a hydrophobic methacrylate backbone and hydrophilic ethylene oxide (EO) side groups with highly branched architecture. The highly branched architecture with a high density of oligo EO moieties enhances the solubility of the polymer in water.

Application

  • Drug delivery- enhances the stability and delivery of siRNA and eliminates PEG antigenicity
  • Biosensor coatings- provides an anti-fouling surface
  • Stimuli-responsive hydrogels for tissue engineering, drug delivery, and other biomedical applications

Features and Benefits

  • Highly branched architecture and high density of oligo ethylene oxide moieties
  • Water soluble
  • Nonfouling and thermo-responsive behaviors
  • Viable alternative to PEG in biological and biomaterial applications
  • Lower critical solution temperature (LCST) behavior

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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