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Key Documents

659630

Sigma-Aldrich

Polylactide-block-poly(ethylene glycol)-block-polylactide

PLA average Mn 1,500, PEG average Mn 900

Synonym(s):

PLA-PEG-PLA

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About This Item

Linear Formula:
HO(CHCH3COO)x(CH2CH2O)y(COCHCH3O)zH
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23

form

solid

mol wt

PEG average Mn 900
PLA average Mn 1,500
average Mn (1,500-900-1,500)

degradation timeframe

<12 months

transition temp

Tm 278.5 °C
Tg 7-9 °C

PDI

<1.2

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Application

The PLA average Mn value of 3,000 is a combined total between the two PLA blocks.

Features and Benefits

Biodegradable polymer. Applications include drug encapsulation and drug delivery.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Articles

Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.

Microparticle drug delivery systems have been extensively researched and applied to a wide variety of pharmaceutical and medical applications due to a number of advantages including injectability, local applicability to target tissues and sites, and controlled drug delivery over a given time period.

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

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