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545864

Sigma-Aldrich

(S)-(−)-Aminoglutethimide

97%

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About This Item

Empirical Formula (Hill Notation):
C13H16N2O2
CAS Number:
57288-03-6
Molecular Weight:
232.28
UNSPSC Code:
12352005
PubChem Substance ID:
24878856
NACRES:
NA.22

Assay

97%

optical activity

[α]20/D −160°, c = 1 in methanol

mp

115.5-119.5 °C (lit.)

SMILES string

CC[C@]1(CCC(=O)NC1=O)c2ccc(N)cc2

InChI

1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)/t13-/m0/s1

InChI key

ROBVIMPUHSLWNV-ZDUSSCGKSA-N

Gene Information

human ... CYP17A1(1586) , CYP19A1(1588)

Application

(S)-(−)-Aminoglutethimide can be used:
  • As an internal standard in the separation of the pyridoglutethimide enantiomers using the HPLC technique.
  • In the study of steroid hormones role on human cytomegalovirus replication in adrenocortical cells.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
15330PI

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Marta Trevisan et al.
Journal of cellular physiology, 221(3), 629-641 (2009-08-19)
Following our recent findings on the presence of human cytomegalovirus (HCMV) in the normal human adrenal cortex and in adrenocortical tumors, especially in cortisol-secreting tumors, aim of the present study was to investigate the direct effects of HCMV infection on

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