376353

Z-α-Phosphonoglycine trimethyl ester

97%

• Synonym(s): (±)-Z-α-Phosphonoglycine trimethyl ester, (±)-Methyl 2-benzyloxycarbonylamino-2-(dimethoxyphosphinyl) acetate, (±)-Trimethyl Z-α-phosphonoglycinate
• Linear Formula: (CH₃O)₂P(O)CH(NHCO₂CH₂C₆H₅)CO₂CH₃
• CAS Number: 88568-95-0
• Molecular Weight: 331.26
• Beilstein: 5764460
• MDL number: MFCD00043304
• UNSPSC Code: 12352209
• PubChem Substance ID: 24863436
• NACRES: NA.22

Properties

• Assay: 97%
• reaction suitability: reaction type: solution phase peptide synthesis
• mp: 77-80 °C (lit.)
• application(s): peptide synthesis
• SMILES string: COC(=O)C(NC(=O)OCc1ccccc1)P(=O)(OC)OC
• InChI: 1S/C13H18NO7P/c1-18-12(15)11(22(17,19-2)20-3)14-13(16)21-9-10-7-5-4-6-8-10/h4-8,11H,9H2,1-3H3,(H,14,16)
• InChI key: GSYSFVSGPABNNL-UHFFFAOYSA-N

Description

Application

Starting material for the synthesis of (Z)-dehydroamino acids by Wittig-Horner reaction with aldehydes; the dehydroamino acids can be stereoselectively reduced to amino acids.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves