Skip to Content
Merck
All Photos(1)

Documents

247162

Sigma-Aldrich

Ethyl propionylacetate

97%

Synonym(s):

Ethyl 3-oxovalerate

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
CH3CH2COCH2COOC2H5
CAS Number:
4949-44-4
Molecular Weight:
144.17
Beilstein:
970270
EC Number:
225-593-5
MDL number:
MFCD00009317
UNSPSC Code:
12352100
PubChem Substance ID:
24854855
NACRES:
NA.22

Assay

97%

form

liquid

refractive index

n20/D 1.422 (lit.)

bp

83-84 °C/12 mmHg (lit.)

density

1.012 g/mL at 25 °C (lit.)

SMILES string

CCOC(=O)CC(=O)CC

InChI

1S/C7H12O3/c1-3-6(8)5-7(9)10-4-2/h3-5H2,1-2H3

InChI key

UDRCONFHWYGWFI-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Ethyl propionylacetate reacts with tropolone p-toluenesulfonate in the presence of sodium ethoxide to give 3-propionyl-2H-cyclohepta[b]furan-2-one.

Application

Ethyl propionylacetate has been used in the synthesis of 1-ethyl- and 1-n-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid bearing one or two substituents on the benzene ring.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

172.4 °F - closed cup

Flash Point(C)

78 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

Methyl acetoacetate ReagentPlus®, ≥98.5% (GC)

Sigma-Aldrich

537365

Methyl acetoacetate

Iodomethane contains copper as stabilizer, ReagentPlus®, 99%

Sigma-Aldrich

I8507

Iodomethane

A simple and efficient synthesis of 2-alkylazulenes.
Iwama N, et al.
Tetrahedron Letters, 45(50), 9211-9213 (2004)
R R Martel et al.
Journal of medicinal chemistry, 19(3), 391-395 (1976-03-01)
A series of 37 1-ethyl- and 1-n-propyl-1, 3, 4, 9-tetrahydropyrano[3, 4-b]indole-1-acetic acids bearing one, or two, substituents on the benzene ring has been synthesized via the acid-catalyzed condensation of a substituted tryptophol with ethyl propionylacetate or ethyl butyrylacetate. Antiinflammatory and

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service