126136

Diethyl methylmalonate

99%

• Synonym(s): Methylmalonic acid diethyl ester
• Linear Formula: CH₃CH(COOC₂H₅)₂
• CAS Number: 609-08-5
• Molecular Weight: 174.19
• Beilstein: 637028
• EC Number: 210-175-7
• MDL number: MFCD00009162
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847702
• NACRES: NA.22

Properties

• Assay: 99%
• refractive index: n20/D 1.413 (lit.)
• bp: 198-199 °C (lit.); 78-80 °C/10 mmHg
• density: 1.022 g/mL at 20 °C (lit.)
• SMILES string: CCOC(=O)C(C)C(=O)OCC
• InChI: 1S/C8H14O4/c1-4-11-7(9)6(3)8(10)12-5-2/h6H,4-5H2,1-3H3
• InChI key: UPQZOUHVTJNGFK-UHFFFAOYSA-N

Description

General description

Diethyl methylmalonate reacts with 2-cyclohexenone under abnormal Michael conditions form 2-(3-oxocyclohexyl)-2-cyclohexenone. It causes the alkylation of poly(chloromethylstyrene) during pahse transfer catalysis.

Application

Diethyl methylmalonate was used to investigate the effect of direct supplementation of the medium with di-ester of methylmalonate on erythromycin fermentation in Saccharopolyspora erythraea mutB strain.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 179.6 °F - closed cup
• Flash Point(C): 82 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves