1672600

Tramadol hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): (±)-cis-2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride
• Empirical Formula (Hill Notation): C₁₆H₂₅NO₂ · HCl
• CAS Number: 36282-47-0
• Molecular Weight: 299.84
• MDL number: MFCD00798507
• UNSPSC Code: 41116107
• PubChem Substance ID: 329751360
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: tramadol
• manufacturer/tradename: USP
• drug control: USDEA Schedule IV
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: Cl.COc1cccc(c1)[C@@]2(O)CCCC[C@@H]2CN(C)C
• InChI: 1S/C16H25NO2.ClH/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3;/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3;1H/t14-,16+;/m1./s1
• InChI key: PPKXEPBICJTCRU-XMZRARIVSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Tramadol hydrochloride USP reference standard for use in specified quality tests and assays.

Also used to prepare standard, system suitability, standard stock, and system suitability stock solutions for assay, impurity analysis, and performance tests according to the given below monographs of United States Pharmacopeia (USP):

• Tramadol Hydrochloride and Acetaminophen Tablets
• Tramadol Hydrochloride Extended-Release Tablets
• Tramadol Hydrochloride
• Tramadol Hydrochloride Tablets

Biochem/physiol Actions

Opioid analgesic; P450 substrate.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS06,GHS09
• Signal Word: Danger
• Hazard Statements: H301 - H336 - H411
• Precautionary Statements: P261 - P264 - P271 - P273 - P301 + P310 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 2 - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable