1341001

Indomethacin

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid
• Empirical Formula (Hill Notation): C₁₉H₁₆ClNO₄
• CAS Number: 53-86-1
• Molecular Weight: 357.79
• Beilstein: 497341
• MDL number: MFCD00057095
• UNSPSC Code: 41116107
• PubChem Substance ID: 329750165
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: indomethacin
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: COc1ccc2n(c(C)c(CC(O)=O)c2c1)C(=O)c3ccc(Cl)cc3
• InChI: 1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)
• InChI key: CGIGDMFJXJATDK-UHFFFAOYSA-N
• Gene Information: human ... PTGS1(5742) , PTGS2(5743)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Indomethacin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Indomethacin Capsules
• Indomethacin Extended-Release Capsules
• Indomethacin for Injection
• Indomethacin Oral Suspension
• Indomethacin Sodium
• Indomethacin Suppositories

Biochem/physiol Actions

Cyclooxygenase (COX) inhibitor that is relatively selective for COX-1.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H300
• Precautionary Statements: P301 + P330 + P331 + P310
• Hazard Classifications: Acute Tox. 1 Oral
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable